Antibiotic with Amoxicillin and Clavulanic acid
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Shipping :  Worldwide

EXP: 05/2021



Active ingredients:                                                mg per tablet
Amoxicillin                                                                200.0
(as Amoxicillin Trihydrate)                                       229.5
Clavulanic acid                                                           50.0
(as Potassium Clavulanate)                                     59.5
Erythrosine Lake (E127)                                           17.5

  •  Target species

Cats and dogs.
 Indications for use, specifying the target species
 The product has been shown to be effective in treating a wide range of diseases of cats and dogs including: Skin disease (including deep and superficial pyodermas); soft tissue infections (abscesses and anal sacculitis); dental infections (e.g. gingivitis); urinary tract infections; respiratory disease (involving upper and lower respiratory tract); enteritis.

  •  Contraindications

 The product should not be given to rabbits, guinea pigs, hamsters or gerbils. Caution is advised in their use in any other very small herbivores.
   Special precautions for use

  •  Special precautions for use in animals

                   Special precautions to be taken by the person administering the veterinary medicinal product to animals
 Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.
 1)            Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.
2)            Handle this product with great care to avoid exposure, taking all recommended precautions.
3)            If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention.
4)            Wash hands after use.

  •   Use during pregnancy, lactation or lay

 The product can be safely used in pregnant and lactating animals.

  •    Interaction with other medicinal products and other forms of interaction

 None known.

  •    Amounts to be administered and administration route  

Administration: by the oral route.
Dosage rate: 12.5 mg/kg bodyweight.
Dosage frequency: The following table is intended as a guide to dispensing at the standard dose rate of 12.5 mg/kg , twice daily.
Bodyweight (kg)
Number of tablets per day, twice daily

Bodyweight (kg)

Number of tablets per day, twice daily


50 mg

250 mg

1 - 2



3 - 5



6 - 9



10 - 13



14 - 18



19 - 25



26 - 35


1 ½

36 - 49






Example: 20 kg dog - 1/2 tabl. in the morning and 1/2 tabl in the evening . 
For the majority of infections including those of the skin, urinary tract and gastrointestinal tract, the above dosage regime is effective.  Refractory cases however particularly of the respiratory tract have shown improved cure rates by doubling the dose to 25mg/kg bodyweight twice daily.
Duration of therapy:
Routine cases involving all indications:
The majority of these cases respond to between 5 and 7 days therapy.
 Chronic or refractory cases:
In these cases, where there is considerable tissue damage, a longer course of therapy maybe required in that it allows sufficient time for damaged tissue to repair.  Based on clinical trials, the following durations are suggested as guidelines:
    Chronic skin disease          10 – 12 days
   Chronic cystitis         10 – 28 days
   Respiratory disease   8 – 10 days
 The product is effective against Klebsiella infections found in veterinary practice, but it is not indicated for cases involving Pseudomonas species.
Tablets are often accepted from the hand, even by sick dogs and cats. Alternatively, the tablets may be crumbled and added to a little food.

  • Overdose (symptoms, emergency procedures, antidotes), if necessary

 The product is of low order toxicity to the target species. No adverse side effects are to be expected from accidental overdose.


The ingredients have a notably broad spectrum of bactericidal activity against bacteria commonly found in cats and dogs.
Resistance to many antibiotics is caused by ß-lactamase enzymes which destroy the antibiotic before it can act on the bacteria themselves. The clavulanate counteracts this defence mechanism by inactivating the ß-lactamases, thus rendering the organisms sensitive to amoxicillin’s rapid bactericidal effect, at concentrations readily attainable in the body.
In vitro Synulox is active against a wide range of clinically important aerobic and anaerobic bacteria including:
Gram-positive: Staphylococci (including ß-lactamase producing strains); Clostridia; Arcanobacteria (Corynebacteria); Peptostreptococcus spp; Streptococci.

Gram-negative: Bacteroides spp (including ß-lactamase producing strains); Escherichia coli (including most ß-lactamase producing strains); Salmonellae (including ß-lactamase producing strains); Bordetella bronchiseptica; Campylobacter spp; Fusobacterium necrophorum; Klebsiellae; Pasteurellae; Proteus spp.

Shipping : Worldwide

EXP: 08/2019



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